The founding purpose then was: "to develop a mechanism by which the two hospitals will be able to collaboratively plan to maximize the use of existing and new health care resources available to the area and to provide the best quality hospital care to the residents of North Simcoe".

When in 1911, Penetanguishene built its own hospital, the name was shortened accordingly.

In the little isolated hospital building in Sunnyside, cows and chickens were kept and a large garden helped supply the kitchen.

Increased activity has resulted in two major expansions since 1954; the addition of a new emergency, outpatient and physiotherapy unit in 1973 and a chronic/rehabilitation unit in 1981.

In September 1992 the hospital was approved by the Ministry of Health to operate as a regional rehabilitation centre and 15 beds were reclassified for this purpose.

A capital campaign began in 1988, managed by the newly formed Huronia District Hospital Foundation raised over $2 million to make the necessary changes to HDH to meet volume increases.

The Penetanguishene site has a culture rich in history and faith dating back to the very beginning of the healing ministry in Canada.In the heart of what is known as Huronia, French voyageurs traveled as early as 1610, soon to be followed by Jesuits missionaries who brought the gospel message and established their healing ministry, opening the first hospital in Ontario at Ste. In the early 1900's a diphtheria epidemic struck and the need for adequate hospital services and accommodations became clear.A small group of public spirited individuals along with the town's physicians saw their dream become a reality when on April 14, 1911 The Penetanguishene Hospital was incorporated.That solution included the integration of the two hospital sites into one secular organization and the divestment of the neighbouring psychiatric hospital from the province to the CHAO sponsored Penetanguishene General Hospital Inc.Georgian Bay General Hospital was the name selected following a community-wide process and open vote in December 2009.The organization's vision to provide Exceptional Care, Every Person, Every Time, was announced at the same time.